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BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer’s disease

Alzheimer’s disease (AD) is a chronic progressive degenerative disease of the nervous system. Its pathogenesis is complex and is related to the abnormal expression of the amyloid β (Aβ), APP, and Tau proteins. Evidence has demonstrated that bone morphogenetic protein 4 (BMP4) is highly expressed in...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqing, Li, Juan, Ma, Li, Xu, Hui, Cao, Yun, Liang, Wei, Ma, Jia, Wang, Z. Peter, Li, Yuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961014/
https://www.ncbi.nlm.nih.gov/pubmed/33723239
http://dx.doi.org/10.1038/s41420-021-00435-x

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