Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

Non-small cell lung cancer (NSCLC) has limited treatment options. Expression of the RNA-binding protein (RBP) Musashi-2 (MSI2) is elevated in a subset of non-small cell lung cancer (NSCLC) tumors upon progression, and drives NSCLC metastasis. We evaluated the mechanism of MSI2 action in NSCLC to gai...

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Detalles Bibliográficos
Autores principales: Makhov, Petr, Bychkov, Igor, Faezov, Bulat, Deneka, Alexander, Kudinov, Alexander, Nicolas, Emmanuelle, Brebion, Rohan, Avril, Eleanor, Cai, Kathy Q., Kharin, Leonid V., Voloshin, Mark, Frantsiyants, Elena, Karnaukhov, Nikolay, Kit, Oleg I., Topchu, Iuliia, Fazliyeva, Rushaniya, Nikonova, Anna S., Serebriiskii, Ilya G., Borghaei, Hossein, Edelman, Martin, Dulaimi, Essel, Golemis, Erica A., Boumber, Yanis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961039/
https://www.ncbi.nlm.nih.gov/pubmed/33723247
http://dx.doi.org/10.1038/s41389-021-00317-y

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