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Binding of calcium and magnesium to human cardiac troponin C
Cardiac muscle thin filaments are composed of actin, tropomyosin, and troponin that change conformation in response to Ca(2+) binding, triggering muscle contraction. Human cardiac troponin C (cTnC) is the Ca(2+)-sensing component of the thin filament. It contains structural sites (III/IV) that bind...
Autores principales: | Rayani, Kaveh, Seffernick, Justin, Li, Alison Yueh, Davis, Jonathan P., Spuches, Anne Marie, Van Petegem, Filip, Solaro, R. John, Lindert, Steffen, Tibbits, Glen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961095/ https://www.ncbi.nlm.nih.gov/pubmed/33548225 http://dx.doi.org/10.1016/j.jbc.2021.100350 |
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