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Structural basis of fast- and slow-severing actin–cofilactin boundaries
Members of the ADF/cofilin family of regulatory proteins bind actin filaments cooperatively, locally change actin subunit conformation and orientation, and sever filaments at “boundaries” between bare and cofilin-occupied segments. A cluster of bound cofilin introduces two distinct classes of bounda...
Autores principales: | Hocky, Glen M., Sindelar, Charles V., Cao, Wenxiang, Voth, Gregory A., De La Cruz, Enrique M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961102/ https://www.ncbi.nlm.nih.gov/pubmed/33508320 http://dx.doi.org/10.1016/j.jbc.2021.100337 |
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