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Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review

INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an...

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Autores principales: Zhang, Jing, He, Xiuchao, Yu, Wenying, Ying, Fuming, Cai, Jun, Deng, Shengde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961132/
https://www.ncbi.nlm.nih.gov/pubmed/33737841
http://dx.doi.org/10.2147/RMHP.S296172
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author Zhang, Jing
He, Xiuchao
Yu, Wenying
Ying, Fuming
Cai, Jun
Deng, Shengde
author_facet Zhang, Jing
He, Xiuchao
Yu, Wenying
Ying, Fuming
Cai, Jun
Deng, Shengde
author_sort Zhang, Jing
collection PubMed
description INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an unusual case of a 62-year-old man who presented with right upper quadrant pain. The inflammatory indicators were elevated, and alkaline phosphatase (AKP), carbohydrate antigen (CA-199 and CA-125) were slightly increased. Computed tomography images and magnetic resonance images discovered a 7.8 × 7.4 × 6.6 cm mass with irregular radiated and cotton-like tumor bone between the liver and right kidney space. Pathology revealed the mass to be primary exophytic ESOS of the liver. The patient underwent a surgical operation and standard chemotherapy and is still alive with no recurrence and metastasis to date. CONCLUSION: Owing to the rarity of the tumor and the lack of clinical characteristics and specific laboratory indexes, it is difficult to make a correct diagnosis. Medical imaging features mainly behave soft tissue entity with tumor bone composition. Surgical resection combined with adjuvant chemotherapy is the main treatment for ESOS.
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spelling pubmed-79611322021-03-17 Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review Zhang, Jing He, Xiuchao Yu, Wenying Ying, Fuming Cai, Jun Deng, Shengde Risk Manag Healthc Policy Case Report INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an unusual case of a 62-year-old man who presented with right upper quadrant pain. The inflammatory indicators were elevated, and alkaline phosphatase (AKP), carbohydrate antigen (CA-199 and CA-125) were slightly increased. Computed tomography images and magnetic resonance images discovered a 7.8 × 7.4 × 6.6 cm mass with irregular radiated and cotton-like tumor bone between the liver and right kidney space. Pathology revealed the mass to be primary exophytic ESOS of the liver. The patient underwent a surgical operation and standard chemotherapy and is still alive with no recurrence and metastasis to date. CONCLUSION: Owing to the rarity of the tumor and the lack of clinical characteristics and specific laboratory indexes, it is difficult to make a correct diagnosis. Medical imaging features mainly behave soft tissue entity with tumor bone composition. Surgical resection combined with adjuvant chemotherapy is the main treatment for ESOS. Dove 2021-03-11 /pmc/articles/PMC7961132/ /pubmed/33737841 http://dx.doi.org/10.2147/RMHP.S296172 Text en © 2021 Zhang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Zhang, Jing
He, Xiuchao
Yu, Wenying
Ying, Fuming
Cai, Jun
Deng, Shengde
Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title_full Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title_fullStr Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title_full_unstemmed Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title_short Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
title_sort primary exophytic extraskeletal osteosarcoma of the liver: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961132/
https://www.ncbi.nlm.nih.gov/pubmed/33737841
http://dx.doi.org/10.2147/RMHP.S296172
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