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Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review
INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961132/ https://www.ncbi.nlm.nih.gov/pubmed/33737841 http://dx.doi.org/10.2147/RMHP.S296172 |
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author | Zhang, Jing He, Xiuchao Yu, Wenying Ying, Fuming Cai, Jun Deng, Shengde |
author_facet | Zhang, Jing He, Xiuchao Yu, Wenying Ying, Fuming Cai, Jun Deng, Shengde |
author_sort | Zhang, Jing |
collection | PubMed |
description | INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an unusual case of a 62-year-old man who presented with right upper quadrant pain. The inflammatory indicators were elevated, and alkaline phosphatase (AKP), carbohydrate antigen (CA-199 and CA-125) were slightly increased. Computed tomography images and magnetic resonance images discovered a 7.8 × 7.4 × 6.6 cm mass with irregular radiated and cotton-like tumor bone between the liver and right kidney space. Pathology revealed the mass to be primary exophytic ESOS of the liver. The patient underwent a surgical operation and standard chemotherapy and is still alive with no recurrence and metastasis to date. CONCLUSION: Owing to the rarity of the tumor and the lack of clinical characteristics and specific laboratory indexes, it is difficult to make a correct diagnosis. Medical imaging features mainly behave soft tissue entity with tumor bone composition. Surgical resection combined with adjuvant chemotherapy is the main treatment for ESOS. |
format | Online Article Text |
id | pubmed-7961132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-79611322021-03-17 Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review Zhang, Jing He, Xiuchao Yu, Wenying Ying, Fuming Cai, Jun Deng, Shengde Risk Manag Healthc Policy Case Report INTRODUCTION: Primary hepatic extraskeletal osteosarcoma (ESOS) is a rare tumor with no specific clinical manifestations, and little is known about it. Here, we describe an elderly patient with primary hepatic osteosarcoma confirmed by pathology results to raise awareness. CASE REPORT: We report an unusual case of a 62-year-old man who presented with right upper quadrant pain. The inflammatory indicators were elevated, and alkaline phosphatase (AKP), carbohydrate antigen (CA-199 and CA-125) were slightly increased. Computed tomography images and magnetic resonance images discovered a 7.8 × 7.4 × 6.6 cm mass with irregular radiated and cotton-like tumor bone between the liver and right kidney space. Pathology revealed the mass to be primary exophytic ESOS of the liver. The patient underwent a surgical operation and standard chemotherapy and is still alive with no recurrence and metastasis to date. CONCLUSION: Owing to the rarity of the tumor and the lack of clinical characteristics and specific laboratory indexes, it is difficult to make a correct diagnosis. Medical imaging features mainly behave soft tissue entity with tumor bone composition. Surgical resection combined with adjuvant chemotherapy is the main treatment for ESOS. Dove 2021-03-11 /pmc/articles/PMC7961132/ /pubmed/33737841 http://dx.doi.org/10.2147/RMHP.S296172 Text en © 2021 Zhang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Zhang, Jing He, Xiuchao Yu, Wenying Ying, Fuming Cai, Jun Deng, Shengde Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title | Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title_full | Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title_fullStr | Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title_full_unstemmed | Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title_short | Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review |
title_sort | primary exophytic extraskeletal osteosarcoma of the liver: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961132/ https://www.ncbi.nlm.nih.gov/pubmed/33737841 http://dx.doi.org/10.2147/RMHP.S296172 |
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