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Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression

Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell disorders with a poor prognosis, especially for elderly patients. Increasing evidence suggests that alterations in the non-hematopoietic microenvironment (bone marrow niche) can contribute to or initi...

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Detalles Bibliográficos
Autores principales: Weickert, Marie-Theresa, Hecker, Judith S., Buck, Michèle C., Schreck, Christina, Rivière, Jennifer, Schiemann, Matthias, Schallmoser, Katharina, Bassermann, Florian, Strunk, Dirk, Oostendorp, Robert A. J., Götze, Katharina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961144/
https://www.ncbi.nlm.nih.gov/pubmed/33723276
http://dx.doi.org/10.1038/s41598-021-85122-8