Cargando…

Postbiotics as Promising Tools for Cancer Adjuvant Therapy

As many investigations have reported, there is a complicated relation between fermented foods, lactic acid bacteria (LAB), and human health. It seems that bioactive components such as prebiotics, probiotics, and postbiotics are key mediators of the complex and direct association between these factor...

Descripción completa

Detalles Bibliográficos
Autores principales: Homayouni Rad, Aziz, Aghebati Maleki, Leili, Samadi Kafil, Hossein, Fathi Zavoshti, Hamideh, Abbasi, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961229/
https://www.ncbi.nlm.nih.gov/pubmed/33747846
http://dx.doi.org/10.34172/apb.2021.007
_version_ 1783665214089068544
author Homayouni Rad, Aziz
Aghebati Maleki, Leili
Samadi Kafil, Hossein
Fathi Zavoshti, Hamideh
Abbasi, Amin
author_facet Homayouni Rad, Aziz
Aghebati Maleki, Leili
Samadi Kafil, Hossein
Fathi Zavoshti, Hamideh
Abbasi, Amin
author_sort Homayouni Rad, Aziz
collection PubMed
description As many investigations have reported, there is a complicated relation between fermented foods, lactic acid bacteria (LAB), and human health. It seems that bioactive components such as prebiotics, probiotics, and postbiotics are key mediators of the complex and direct association between these factors. LAB activity in the matrix of fermented foods and improving their growth by prebiotic compounds ultimately results in the production of bioactive molecules (postbiotics), which possess specific biological and physiological properties. The term "postbiotics" refers to a complex of biological micro- and macromolecules, if consumed in adequate amounts, provides the host with different health-promoting effects. Different reports have suggested that postbiotics possess the ability to moderate the effectiveness of cancer treatment and reduce the side-effects of conventional therapies in cancer patients due to their anti-proliferative, anti-inflammatory and anti-cancer properties. Consequently, postbiotics, for their unique characteristics, have gained great scientific attention and are considered as a novel approach for adjuvant therapy in patients with cancer.
format Online
Article
Text
id pubmed-7961229
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Tabriz University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-79612292021-03-19 Postbiotics as Promising Tools for Cancer Adjuvant Therapy Homayouni Rad, Aziz Aghebati Maleki, Leili Samadi Kafil, Hossein Fathi Zavoshti, Hamideh Abbasi, Amin Adv Pharm Bull Editorial As many investigations have reported, there is a complicated relation between fermented foods, lactic acid bacteria (LAB), and human health. It seems that bioactive components such as prebiotics, probiotics, and postbiotics are key mediators of the complex and direct association between these factors. LAB activity in the matrix of fermented foods and improving their growth by prebiotic compounds ultimately results in the production of bioactive molecules (postbiotics), which possess specific biological and physiological properties. The term "postbiotics" refers to a complex of biological micro- and macromolecules, if consumed in adequate amounts, provides the host with different health-promoting effects. Different reports have suggested that postbiotics possess the ability to moderate the effectiveness of cancer treatment and reduce the side-effects of conventional therapies in cancer patients due to their anti-proliferative, anti-inflammatory and anti-cancer properties. Consequently, postbiotics, for their unique characteristics, have gained great scientific attention and are considered as a novel approach for adjuvant therapy in patients with cancer. Tabriz University of Medical Sciences 2021-01 2020-11-07 /pmc/articles/PMC7961229/ /pubmed/33747846 http://dx.doi.org/10.34172/apb.2021.007 Text en © 2021 The Authors. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers.
spellingShingle Editorial
Homayouni Rad, Aziz
Aghebati Maleki, Leili
Samadi Kafil, Hossein
Fathi Zavoshti, Hamideh
Abbasi, Amin
Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title_full Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title_fullStr Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title_full_unstemmed Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title_short Postbiotics as Promising Tools for Cancer Adjuvant Therapy
title_sort postbiotics as promising tools for cancer adjuvant therapy
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961229/
https://www.ncbi.nlm.nih.gov/pubmed/33747846
http://dx.doi.org/10.34172/apb.2021.007
work_keys_str_mv AT homayouniradaziz postbioticsaspromisingtoolsforcanceradjuvanttherapy
AT aghebatimalekileili postbioticsaspromisingtoolsforcanceradjuvanttherapy
AT samadikafilhossein postbioticsaspromisingtoolsforcanceradjuvanttherapy
AT fathizavoshtihamideh postbioticsaspromisingtoolsforcanceradjuvanttherapy
AT abbasiamin postbioticsaspromisingtoolsforcanceradjuvanttherapy