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Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin
Purpose: Isatin (IS) is a synthetically significant heterocyclic moiety with an influential pharmacodynamic indole nucleus and hence the electrocatalytic property of has been investigated. Methods: The electrochemical analysis was demonstrated by cyclic voltammetry (CV) in the potential window of 0....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961235/ https://www.ncbi.nlm.nih.gov/pubmed/33747858 http://dx.doi.org/10.34172/apb.2021.012 |
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author | Monnappa, Amrutha Balliamada Manjunatha, Jamballi Gangadharappa Bhatt, Aarti Sripathi Malini, Kodi |
author_facet | Monnappa, Amrutha Balliamada Manjunatha, Jamballi Gangadharappa Bhatt, Aarti Sripathi Malini, Kodi |
author_sort | Monnappa, Amrutha Balliamada |
collection | PubMed |
description | Purpose: Isatin (IS) is a synthetically significant heterocyclic moiety with an influential pharmacodynamic indole nucleus and hence the electrocatalytic property of has been investigated. Methods: The electrochemical analysis was demonstrated by cyclic voltammetry (CV) in the potential window of 0.2 V to 1.4 V using sodium dodecyl sulfate (SDS) modified carbon nano tube paste electrode (SDSMCNTPE) over a pH range of 6 to 8.5 in 0.2 M phosphate buffer solution (PBS). Surface morphology was studied by using Field emission-scanning electron microscopy (FESEM). Results: The CV study discloses that under ideal condition oxidation of IS arises at a potential of 0.970 V accompanied with an exceptional stability, selectivity and sensitivity for the resultant SDSMCNTPE contrasting to bare carbon nano tube paste electrode (BCNTPE). Individual parameters like electrode surface area, effect of surfactant, detection limit, simultaneous detection of IS and resorcinol (RC) were studied at a scan rate of 0.1 V/s. Scan rate study uncovers the process is diffusion controlled. The oxidation peak current amplified linearly with the surge in concentration of IS under ideal condition. Detection limit (LOD) and limit of quantification (LOQ) in the solution of optimum pH (7.5) at a scan rate of 0.100V/s is 2.4×10(-7) M and 8.2 × 10(-7) M respectively. Conclusion: The proposed electrode portrays excellent repeatability, reproducibility and reliability to resistant electrode fouling. |
format | Online Article Text |
id | pubmed-7961235 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-79612352021-03-19 Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin Monnappa, Amrutha Balliamada Manjunatha, Jamballi Gangadharappa Bhatt, Aarti Sripathi Malini, Kodi Adv Pharm Bull Research Article Purpose: Isatin (IS) is a synthetically significant heterocyclic moiety with an influential pharmacodynamic indole nucleus and hence the electrocatalytic property of has been investigated. Methods: The electrochemical analysis was demonstrated by cyclic voltammetry (CV) in the potential window of 0.2 V to 1.4 V using sodium dodecyl sulfate (SDS) modified carbon nano tube paste electrode (SDSMCNTPE) over a pH range of 6 to 8.5 in 0.2 M phosphate buffer solution (PBS). Surface morphology was studied by using Field emission-scanning electron microscopy (FESEM). Results: The CV study discloses that under ideal condition oxidation of IS arises at a potential of 0.970 V accompanied with an exceptional stability, selectivity and sensitivity for the resultant SDSMCNTPE contrasting to bare carbon nano tube paste electrode (BCNTPE). Individual parameters like electrode surface area, effect of surfactant, detection limit, simultaneous detection of IS and resorcinol (RC) were studied at a scan rate of 0.1 V/s. Scan rate study uncovers the process is diffusion controlled. The oxidation peak current amplified linearly with the surge in concentration of IS under ideal condition. Detection limit (LOD) and limit of quantification (LOQ) in the solution of optimum pH (7.5) at a scan rate of 0.100V/s is 2.4×10(-7) M and 8.2 × 10(-7) M respectively. Conclusion: The proposed electrode portrays excellent repeatability, reproducibility and reliability to resistant electrode fouling. Tabriz University of Medical Sciences 2021-01 2020-11-07 /pmc/articles/PMC7961235/ /pubmed/33747858 http://dx.doi.org/10.34172/apb.2021.012 Text en © 2021 The Authors. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers. |
spellingShingle | Research Article Monnappa, Amrutha Balliamada Manjunatha, Jamballi Gangadharappa Bhatt, Aarti Sripathi Malini, Kodi Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title | Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title_full | Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title_fullStr | Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title_full_unstemmed | Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title_short | Sodium Dodecyl Sulfate Modified Carbon Nano Tube Paste Electrode for Sensitive Cyclic Voltammetry Determination of Isatin |
title_sort | sodium dodecyl sulfate modified carbon nano tube paste electrode for sensitive cyclic voltammetry determination of isatin |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961235/ https://www.ncbi.nlm.nih.gov/pubmed/33747858 http://dx.doi.org/10.34172/apb.2021.012 |
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