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Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry

Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-A...

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Autores principales: Kiliszek, Marek, Uziębło-Życzkowska, Beata, Gorczyca, Iwona, Maciorowska, Małgorzata, Jelonek, Olga, Wożakowska-Kapłon, Beata, Wójcik, Maciej, Błaszczyk, Robert, Gawałko, Monika, Kapłon-Cieślicka, Agnieszka, Tokarek, Tomasz, Rajtar-Salwa, Renata, Bil, Jacek, Wojewódzki, Michał, Szpotowicz, Anna, Krzciuk, Małgorzata, Bednarski, Janusz, Bakuła-Ostalska, Elwira, Tomaszuk-Kazberuk, Anna, Szyszkowska, Anna, Wełnicki, Marcin, Mamcarz, Artur, Krzesiński, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961425/
https://www.ncbi.nlm.nih.gov/pubmed/33807883
http://dx.doi.org/10.3390/jcm10051091
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author Kiliszek, Marek
Uziębło-Życzkowska, Beata
Gorczyca, Iwona
Maciorowska, Małgorzata
Jelonek, Olga
Wożakowska-Kapłon, Beata
Wójcik, Maciej
Błaszczyk, Robert
Gawałko, Monika
Kapłon-Cieślicka, Agnieszka
Tokarek, Tomasz
Rajtar-Salwa, Renata
Bil, Jacek
Wojewódzki, Michał
Szpotowicz, Anna
Krzciuk, Małgorzata
Bednarski, Janusz
Bakuła-Ostalska, Elwira
Tomaszuk-Kazberuk, Anna
Szyszkowska, Anna
Wełnicki, Marcin
Mamcarz, Artur
Krzesiński, Paweł
author_facet Kiliszek, Marek
Uziębło-Życzkowska, Beata
Gorczyca, Iwona
Maciorowska, Małgorzata
Jelonek, Olga
Wożakowska-Kapłon, Beata
Wójcik, Maciej
Błaszczyk, Robert
Gawałko, Monika
Kapłon-Cieślicka, Agnieszka
Tokarek, Tomasz
Rajtar-Salwa, Renata
Bil, Jacek
Wojewódzki, Michał
Szpotowicz, Anna
Krzciuk, Małgorzata
Bednarski, Janusz
Bakuła-Ostalska, Elwira
Tomaszuk-Kazberuk, Anna
Szyszkowska, Anna
Wełnicki, Marcin
Mamcarz, Artur
Krzesiński, Paweł
author_sort Kiliszek, Marek
collection PubMed
description Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-AF) registry). Consecutive hospitalized AF patients over 18 years of age were enrolled at ten centers. The data were collected for two weeks during each month of 2019. Results: A total of 2785 patients were analyzed, of whom 1360 were asymptomatic (48.8%). Asymptomatic patients were more frequently observed to have coronary artery disease (57.5% vs. 49.1%, p < 0.0001), heart failure with preserved ejection fraction (39.8% vs. 26.5%, p < 0.0001), a previous thromboembolic event (18.2% vs. 13.1%, p = 0.0002), and paroxysmal AF (52.3% vs. 45.2%, p = 0.0002). In multivariate analysis, history of electrical cardioversion, paroxysmal AF, heart failure, coronary artery disease, previous thromboembolic event, and higher left ventricular ejection fraction were predictors of a lack of AF symptoms. First-diagnosed AF was a predictor of AF symptoms. Conclusions: In comparison to symptomatic patients, more of those hospitalized with asymptomatic AF had been previously diagnosed with this arrhythmia and other cardiovascular diseases. However, they presented with better left ventricular function and were more frequently treated with cardiovascular medicines.
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spelling pubmed-79614252021-03-17 Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry Kiliszek, Marek Uziębło-Życzkowska, Beata Gorczyca, Iwona Maciorowska, Małgorzata Jelonek, Olga Wożakowska-Kapłon, Beata Wójcik, Maciej Błaszczyk, Robert Gawałko, Monika Kapłon-Cieślicka, Agnieszka Tokarek, Tomasz Rajtar-Salwa, Renata Bil, Jacek Wojewódzki, Michał Szpotowicz, Anna Krzciuk, Małgorzata Bednarski, Janusz Bakuła-Ostalska, Elwira Tomaszuk-Kazberuk, Anna Szyszkowska, Anna Wełnicki, Marcin Mamcarz, Artur Krzesiński, Paweł J Clin Med Article Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-AF) registry). Consecutive hospitalized AF patients over 18 years of age were enrolled at ten centers. The data were collected for two weeks during each month of 2019. Results: A total of 2785 patients were analyzed, of whom 1360 were asymptomatic (48.8%). Asymptomatic patients were more frequently observed to have coronary artery disease (57.5% vs. 49.1%, p < 0.0001), heart failure with preserved ejection fraction (39.8% vs. 26.5%, p < 0.0001), a previous thromboembolic event (18.2% vs. 13.1%, p = 0.0002), and paroxysmal AF (52.3% vs. 45.2%, p = 0.0002). In multivariate analysis, history of electrical cardioversion, paroxysmal AF, heart failure, coronary artery disease, previous thromboembolic event, and higher left ventricular ejection fraction were predictors of a lack of AF symptoms. First-diagnosed AF was a predictor of AF symptoms. Conclusions: In comparison to symptomatic patients, more of those hospitalized with asymptomatic AF had been previously diagnosed with this arrhythmia and other cardiovascular diseases. However, they presented with better left ventricular function and were more frequently treated with cardiovascular medicines. MDPI 2021-03-05 /pmc/articles/PMC7961425/ /pubmed/33807883 http://dx.doi.org/10.3390/jcm10051091 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kiliszek, Marek
Uziębło-Życzkowska, Beata
Gorczyca, Iwona
Maciorowska, Małgorzata
Jelonek, Olga
Wożakowska-Kapłon, Beata
Wójcik, Maciej
Błaszczyk, Robert
Gawałko, Monika
Kapłon-Cieślicka, Agnieszka
Tokarek, Tomasz
Rajtar-Salwa, Renata
Bil, Jacek
Wojewódzki, Michał
Szpotowicz, Anna
Krzciuk, Małgorzata
Bednarski, Janusz
Bakuła-Ostalska, Elwira
Tomaszuk-Kazberuk, Anna
Szyszkowska, Anna
Wełnicki, Marcin
Mamcarz, Artur
Krzesiński, Paweł
Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title_full Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title_fullStr Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title_full_unstemmed Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title_short Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
title_sort symptomatic and asymptomatic patients in the polish atrial fibrillation (pol-af) registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961425/
https://www.ncbi.nlm.nih.gov/pubmed/33807883
http://dx.doi.org/10.3390/jcm10051091
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