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Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry
Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-A...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961425/ https://www.ncbi.nlm.nih.gov/pubmed/33807883 http://dx.doi.org/10.3390/jcm10051091 |
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author | Kiliszek, Marek Uziębło-Życzkowska, Beata Gorczyca, Iwona Maciorowska, Małgorzata Jelonek, Olga Wożakowska-Kapłon, Beata Wójcik, Maciej Błaszczyk, Robert Gawałko, Monika Kapłon-Cieślicka, Agnieszka Tokarek, Tomasz Rajtar-Salwa, Renata Bil, Jacek Wojewódzki, Michał Szpotowicz, Anna Krzciuk, Małgorzata Bednarski, Janusz Bakuła-Ostalska, Elwira Tomaszuk-Kazberuk, Anna Szyszkowska, Anna Wełnicki, Marcin Mamcarz, Artur Krzesiński, Paweł |
author_facet | Kiliszek, Marek Uziębło-Życzkowska, Beata Gorczyca, Iwona Maciorowska, Małgorzata Jelonek, Olga Wożakowska-Kapłon, Beata Wójcik, Maciej Błaszczyk, Robert Gawałko, Monika Kapłon-Cieślicka, Agnieszka Tokarek, Tomasz Rajtar-Salwa, Renata Bil, Jacek Wojewódzki, Michał Szpotowicz, Anna Krzciuk, Małgorzata Bednarski, Janusz Bakuła-Ostalska, Elwira Tomaszuk-Kazberuk, Anna Szyszkowska, Anna Wełnicki, Marcin Mamcarz, Artur Krzesiński, Paweł |
author_sort | Kiliszek, Marek |
collection | PubMed |
description | Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-AF) registry). Consecutive hospitalized AF patients over 18 years of age were enrolled at ten centers. The data were collected for two weeks during each month of 2019. Results: A total of 2785 patients were analyzed, of whom 1360 were asymptomatic (48.8%). Asymptomatic patients were more frequently observed to have coronary artery disease (57.5% vs. 49.1%, p < 0.0001), heart failure with preserved ejection fraction (39.8% vs. 26.5%, p < 0.0001), a previous thromboembolic event (18.2% vs. 13.1%, p = 0.0002), and paroxysmal AF (52.3% vs. 45.2%, p = 0.0002). In multivariate analysis, history of electrical cardioversion, paroxysmal AF, heart failure, coronary artery disease, previous thromboembolic event, and higher left ventricular ejection fraction were predictors of a lack of AF symptoms. First-diagnosed AF was a predictor of AF symptoms. Conclusions: In comparison to symptomatic patients, more of those hospitalized with asymptomatic AF had been previously diagnosed with this arrhythmia and other cardiovascular diseases. However, they presented with better left ventricular function and were more frequently treated with cardiovascular medicines. |
format | Online Article Text |
id | pubmed-7961425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79614252021-03-17 Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry Kiliszek, Marek Uziębło-Życzkowska, Beata Gorczyca, Iwona Maciorowska, Małgorzata Jelonek, Olga Wożakowska-Kapłon, Beata Wójcik, Maciej Błaszczyk, Robert Gawałko, Monika Kapłon-Cieślicka, Agnieszka Tokarek, Tomasz Rajtar-Salwa, Renata Bil, Jacek Wojewódzki, Michał Szpotowicz, Anna Krzciuk, Małgorzata Bednarski, Janusz Bakuła-Ostalska, Elwira Tomaszuk-Kazberuk, Anna Szyszkowska, Anna Wełnicki, Marcin Mamcarz, Artur Krzesiński, Paweł J Clin Med Article Background: Atrial fibrillation (AF) can cause severe symptoms, but it is frequently asymptomatic. We aimed to compare the clinical features of patients with asymptomatic and symptomatic AF. Methods: A prospective, observational, multicenter study was performed (the Polish Atrial Fibrillation (POL-AF) registry). Consecutive hospitalized AF patients over 18 years of age were enrolled at ten centers. The data were collected for two weeks during each month of 2019. Results: A total of 2785 patients were analyzed, of whom 1360 were asymptomatic (48.8%). Asymptomatic patients were more frequently observed to have coronary artery disease (57.5% vs. 49.1%, p < 0.0001), heart failure with preserved ejection fraction (39.8% vs. 26.5%, p < 0.0001), a previous thromboembolic event (18.2% vs. 13.1%, p = 0.0002), and paroxysmal AF (52.3% vs. 45.2%, p = 0.0002). In multivariate analysis, history of electrical cardioversion, paroxysmal AF, heart failure, coronary artery disease, previous thromboembolic event, and higher left ventricular ejection fraction were predictors of a lack of AF symptoms. First-diagnosed AF was a predictor of AF symptoms. Conclusions: In comparison to symptomatic patients, more of those hospitalized with asymptomatic AF had been previously diagnosed with this arrhythmia and other cardiovascular diseases. However, they presented with better left ventricular function and were more frequently treated with cardiovascular medicines. MDPI 2021-03-05 /pmc/articles/PMC7961425/ /pubmed/33807883 http://dx.doi.org/10.3390/jcm10051091 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kiliszek, Marek Uziębło-Życzkowska, Beata Gorczyca, Iwona Maciorowska, Małgorzata Jelonek, Olga Wożakowska-Kapłon, Beata Wójcik, Maciej Błaszczyk, Robert Gawałko, Monika Kapłon-Cieślicka, Agnieszka Tokarek, Tomasz Rajtar-Salwa, Renata Bil, Jacek Wojewódzki, Michał Szpotowicz, Anna Krzciuk, Małgorzata Bednarski, Janusz Bakuła-Ostalska, Elwira Tomaszuk-Kazberuk, Anna Szyszkowska, Anna Wełnicki, Marcin Mamcarz, Artur Krzesiński, Paweł Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title | Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title_full | Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title_fullStr | Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title_full_unstemmed | Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title_short | Symptomatic and Asymptomatic Patients in the Polish Atrial Fibrillation (POL-AF) Registry |
title_sort | symptomatic and asymptomatic patients in the polish atrial fibrillation (pol-af) registry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961425/ https://www.ncbi.nlm.nih.gov/pubmed/33807883 http://dx.doi.org/10.3390/jcm10051091 |
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