Enantioselective Synthesis of a New Non-Natural Gabosine

The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol. Further chemical transformations to introduce additional functionality and chirality to the molecule were also a...

Descripción completa

Detalles Bibliográficos
Autores principales: Colobbio, Maximiliano, Pandolfi, Enrique, Schapiro, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961443/
https://www.ncbi.nlm.nih.gov/pubmed/33800731
http://dx.doi.org/10.3390/molecules26051423
Descripción
Sumario:The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol. Further chemical transformations to introduce additional functionality and chirality to the molecule were also accomplished.

Ejemplares similares