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Adverse Prognostic Impact of the KIT D816V Transcriptional Activity in Advanced Systemic Mastocytosis

In systemic mastocytosis (SM), qualitative and serial quantitative assessment of the KIT D816V mutation is of diagnostic and prognostic relevance. We investigated peripheral blood and bone marrow samples of 161 patients (indolent SM (ISM), n = 40; advanced SM, AdvSM, n = 121) at referral and during...

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Detalles Bibliográficos
Autores principales: Naumann, Nicole, Lübke, Johannes, Baumann, Sofie, Schwaab, Juliana, Hoffmann, Oliver, Kreil, Sebastian, Dangelo, Vito, Reiter, Lukas, Bugert, Peter, Kristensen, Thomas, Sotlar, Karl, Haselmann, Verena, Schneider, Sven, Metzgeroth, Georgia, Weiss, Christel, Popp, Henning D., Fabarius, Alice, Hofmann, Wolf-Karsten, Cross, Nicholas C. P., Reiter, Andreas, Jawhar, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961551/
https://www.ncbi.nlm.nih.gov/pubmed/33806359
http://dx.doi.org/10.3390/ijms22052562