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Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids

The present study aimed to synthesize novel polycationic polymers composed of N-substituted L-2,3-diaminopropionic acid residues (DAPEGs) and investigate their cell permeability, cytotoxicity, and DNA-binding ability. The most efficient cell membrane-penetrating compounds (O2Oc-Dap(GO2)(n)-O2Oc-NH(2...

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Detalles Bibliográficos
Autores principales:	Romanowska, Anita, Węgrzyn, Katarzyna, Bury, Katarzyna, Sikorska, Emilia, Gnatek, Aleksandra, Piwkowska, Agnieszka, Konieczny, Igor, Lesner, Adam, Wysocka, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961587/ https://www.ncbi.nlm.nih.gov/pubmed/33806461 http://dx.doi.org/10.3390/ijms22052571

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