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From antibody specificity to T cell recognition

Landsteiner’s definition of human blood groups and the genetic rules that govern blood transfusion represents a milestone in human genetics and a historic event in public health. His research into the specificity of serological reactions, although less well known, has had a critical influence on the...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Jung, Cantor, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961596/
https://www.ncbi.nlm.nih.gov/pubmed/33710256
http://dx.doi.org/10.1084/jem.20202038
Descripción
Sumario:Landsteiner’s definition of human blood groups and the genetic rules that govern blood transfusion represents a milestone in human genetics and a historic event in public health. His research into the specificity of serological reactions, although less well known, has had a critical influence on the development of contemporary views on immune recognition, clonal selection, and immunological self-tolerance.