Toxicity Induced by Cytokines, Glucose, and Lipids Increase Apoptosis and Hamper Insulin Secretion in the 1.1E7 Beta Cell-Line

Basic research on types 1 and 2 diabetes mellitus require early stage studies using beta cells or cell lines, ideally of human origin and with preserved insulin secretion in response to glucose. The 1.1E7 cells are a hybrid cell line resulting from the electrofusion of dispersed human islets and PAN...

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Detalles Bibliográficos
Autores principales: Diaz-Ganete, Antonia, Quiroga-de-Castro, Aranzazu, Mateos, Rosa M., Medina, Francisco, Segundo, Carmen, Lechuga-Sancho, Alfonso M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961802/
https://www.ncbi.nlm.nih.gov/pubmed/33806355
http://dx.doi.org/10.3390/ijms22052559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961802/
https://www.ncbi.nlm.nih.gov/pubmed/33806355
http://dx.doi.org/10.3390/ijms22052559

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