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Effective microwave-assisted approach to 1,2,3-triazolobenzodiazepinones via tandem Ugi reaction/catalyst-free intramolecular azide–alkyne cycloaddition

A novel catalyst-free synthetic approach to 1,2,3-triazolobenzodiazepinones has been developed and optimized. The Ugi reaction of 2-azidobenzaldehyde, various amines, isocyanides, and acids followed by microwave-assisted intramolecular azide–alkyne cycloaddition (IAAC) gave a series of target hetero...

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Detalles Bibliográficos
Autores principales:	Mazur, Maryna O, Zhelavskyi, Oleksii S, Zviagin, Eugene M, Shishkina, Svitlana V, Musatov, Vladimir I, Kolosov, Maksim A, Shvets, Elena H, Andryushchenko, Anna Yu, Chebanov, Valentyn A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2021
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961865/ https://www.ncbi.nlm.nih.gov/pubmed/33777243 http://dx.doi.org/10.3762/bjoc.17.57

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