Allele-Specific Knockout by CRISPR/Cas to Treat Autosomal Dominant Retinitis Pigmentosa Caused by the G56R Mutation in NR2E3

Retinitis pigmentosa (RP) is an inherited retinal dystrophy that causes progressive vision loss. The G56R mutation in NR2E3 is the second most common mutation causing autosomal dominant (ad) RP, a transcription factor that is essential for photoreceptor development and maintenance. The G56R variant...

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Detalles Bibliográficos
Autores principales: Diakatou, Michalitsa, Dubois, Gregor, Erkilic, Nejla, Sanjurjo-Soriano, Carla, Meunier, Isabelle, Kalatzis, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961898/
https://www.ncbi.nlm.nih.gov/pubmed/33807610
http://dx.doi.org/10.3390/ijms22052607

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