Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1

In a mouse model of Niemann-Pick disease type C1 (NPC1), a combination therapy (COMBI) of miglustat (MIGLU), the neurosteroid allopregnanolone (ALLO) and the cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (HPßCD) has previously resulted in, among other things, significantly improved motor fun...

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Detalles Bibliográficos
Autores principales: Holzmann, Carsten, Witt, Martin, Rolfs, Arndt, Antipova, Veronica, Wree, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962008/
https://www.ncbi.nlm.nih.gov/pubmed/33802605
http://dx.doi.org/10.3390/ijms22052539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962008/
https://www.ncbi.nlm.nih.gov/pubmed/33802605
http://dx.doi.org/10.3390/ijms22052539

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