Cargando…

Poly(ethylene glycol)-b-poly(1,3-trimethylene carbonate) Amphiphilic Copolymers for Long-Acting Injectables: Synthesis, Non-Acylating Performance and In Vivo Degradation

This article presents the evaluation of diblock and triblock poly(ethylene glycol)-b-poly(1,3-trimethylene carbonate) amphiphilic copolymers (PEG-PTMCs) as excipients for the formulation of long-acting injectables (LAIs). Copolymers were successfully synthesised through bulk ring-opening polymerisat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Curia, Silvio, Ng, Feifei, Cagnon, Marie-Emérentienne, Nicoulin, Victor, Lopez-Noriega, Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962012/ https://www.ncbi.nlm.nih.gov/pubmed/33800940 http://dx.doi.org/10.3390/molecules26051438

Ejemplares similares

Poly(ethylene glycol)-b-poly(1,3-trimethylene carbonate) Copolymers for the Formulation of In Situ Forming Depot Long-Acting Injectables
por: Cagnon, Marie-Emérentienne, et al.
Publicado: (2021)

Phase Separation and Elastic Properties of Poly(Trimethylene Terephthalate)-block-poly(Ethylene Oxide) Copolymers
por: Piesowicz, Elżbieta, et al.
Publicado: (2016)

Membranes for Modelling Cardiac Tissue Stiffness In Vitro Based on Poly(trimethylene carbonate) and Poly(ethylene glycol) Polymers
por: Allijn, Iris, et al.
Publicado: (2020)

Thermo-Responsive Polyurethane Hydrogels Based on Poly(ε-caprolactone) Diol and Amphiphilic Polylactide-Poly(Ethylene Glycol) Block Copolymers
por: Hsu, Shan-hui, et al.
Publicado: (2016)

Superparamagnetic Nanocrystals Clustered Using Poly(ethylene glycol)-Crosslinked Amphiphilic Copolymers for the Diagnosis of Liver Cancer
por: Jiang, Ling, et al.
Publicado: (2023)

Novel 4-Arm Poly(Ethylene Glycol)-Block-Poly(Anhydride-Esters) Amphiphilic Copolymer Micelles Loading Curcumin: Preparation, Characterization, and In Vitro Evaluation
por: Lv, Li, et al.
Publicado: (2013)

Interfacial properties and micellization of triblock poly(ethylene glycol)-poly(ε-caprolactone)-polyethyleneimine copolymers
por: Li, Ji, et al.
Publicado: (2020)

Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides
por: Sirsi, Shashank R, et al.
Publicado: (2009)

Non-Isothermal Crystallization Kinetics of Poly(Ethylene Glycol)–Poly(l-Lactide) Diblock Copolymer and Poly(Ethylene Glycol) Homopolymer via Fast-Scan Chip-Calorimeter
por: Chen, Dejia, et al.
Publicado: (2021)

Amphiphilic poly{[α-maleic anhydride-ω-methoxy-poly(ethylene glycol)]-co-(ethyl cyanoacrylate)} graft copolymer nanoparticles as carriers for transdermal drug delivery
por: Xing, Jinfeng, et al.
Publicado: (2009)

Amphiphilic Block Copolymer Microspheres Derived from Castor Oil, Poly(ε-carpolactone), and Poly(ethylene glycol): Preparation, Characterization and Application in Naltrexone Drug Delivery
por: Nerantzaki, Maria, et al.
Publicado: (2018)

On the Mechanisms of the Effects of Ionizing Radiation on Diblock and Random Copolymers of Poly(Lactic Acid) and Poly(Trimethylene Carbonate)
por: Adamus-Wlodarczyk, Agnieszka, et al.
Publicado: (2018)

Amphiphilic Polymer Conetwork Gel Films Based on Tetra-Poly(ethylene Glycol) and Tetra-Poly(ε-Caprolactone)
por: Hagmann, Kevin, et al.
Publicado: (2022)

Paclitaxel-incorporated nanoparticles using block copolymers composed of poly(ethylene glycol)/poly(3-hydroxyoctanoate)
por: Kim, Hyun Yul, et al.
Publicado: (2014)

Thermoresponsive Poly(ε-Caprolactone)-Poly(Ethylene/Propylene Glycol) Copolymers as Injectable Hydrogels for Cell Therapies
por: Brewer, Kyle, et al.
Publicado: (2020)

Hydrophilization of Poly(Caprolactone) Copolymers through Introduction of Oligo(Ethylene Glycol) Moieties
por: Wurth, Jonathan J., et al.
Publicado: (2014)

Preparation and Characterization of Poly(Lactic Acid)/Poly (ethylene glycol)-Poly(propyl glycol)-Poly(ethylene glycol) Blended Nanofiber Membranes for Fog Collection
por: Aijaz, Muhammad Omer, et al.
Publicado: (2022)

Biocompatibility and paclitaxel/cisplatin dual-loading of nanotubes prepared from poly(ethylene glycol)-polylactide-poly(ethylene glycol) triblock copolymers for combination cancer therapy
por: Shen, Xin, et al.
Publicado: (2019)

In vitro and in vivo degradation behavior of poly(trimethylene carbonate-co-d,l-lactic acid) copolymer
por: Ma, Zhengyu, et al.
Publicado: (2017)

In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer
por: Gong, Chang Yang, et al.
Publicado: (2009)

Amphiphilic Block Copolymer of Poly(dimethylsiloxane) and Methoxypolyethylene Glycols for High-Permeable Polysulfone Membrane Preparation
por: Zhang, Lei, et al.
Publicado: (2019)

Cell attachment on poly(3-hydroxybutyrate)-poly(ethylene glycol) copolymer produced by Azotobacter chroococcum 7B
por: Bonartsev, Anton P, et al.
Publicado: (2013)

Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials
por: Ordanini, Stefania, et al.
Publicado: (2019)

Preparation and physicochemical characterization of camptothecin conjugated poly amino ester–methyl ether poly ethylene glycol copolymer
por: Fattahi, Ali, et al.
Publicado: (2018)

Mucoadhesive and Rheological Studies on the Co-Hydrogel Systems of Poly(Ethylene Glycol) Copolymers with Fluoroalkyl and Poly(Acrylic Acid)
por: Sun, Yang, et al.
Publicado: (2021)

Synthesis and characterization of 4-arm star-shaped amphiphilic block copolymers consisting of poly(ethylene oxide) and poly(ε-caprolactone)
por: Bhayo, Adnan Murad, et al.
Publicado: (2018)

Microstructure—Thermal Property Relationships of Poly (Ethylene Glycol-b-Caprolactone) Copolymers and Their Micelles
por: Faisal, Khandokar Sadique, et al.
Publicado: (2022)

Development of Amphotericin B Micellar Formulations Based on Copolymers of Poly(ethylene glycol) and Poly(ε-caprolactone) Conjugated with Retinol
por: Rodriguez, Yeimy J., et al.
Publicado: (2020)

Poly(ethylene glycol)-block-poly(sodium 4-styrenesulfonate) Copolymers as Efficient Zika Virus Inhibitors: In Vitro Studies
por: Botwina, Paweł, et al.
Publicado: (2023)

Multi-Armed Star-Shaped Block Copolymers of Poly(ethylene glycol)-Poly(furfuryl glycidol) as Long Circulating Nanocarriers
por: Nakagawa, Yasuhiro, et al.
Publicado: (2023)

Non-Isothermal Crystallization Kinetics of Poly(ethylene glycol) and Poly(ethylene glycol)-B-Poly(ε-caprolactone) by Flash DSC Analysis
por: Li, Xiaodong, et al.
Publicado: (2021)

Dispersant and Protective Roles of Amphiphilic Poly(ethylene phosphate) Block Copolymers in Polyester/Bone Mineral Composites
por: Nifant’ev, Ilya, et al.
Publicado: (2023)

Influence of Poly(Ethylene Glycol) End Groups on Poly(Ethylene Glycol)-Albumin System Properties as a Potential Degradable Tissue Scaffold
por: Overby, Robyn J., et al.
Publicado: (2018)

Novel lactoferrin-conjugated amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide) copolymer nanobubbles for tumor-targeting ultrasonic imaging
por: Luo, Binhua, et al.
Publicado: (2015)

pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer
por: Tao, Youhua, et al.
Publicado: (2009)

Poly(phenylene ether) Based Amphiphilic Block Copolymers
por: Peters, Edward N.
Publicado: (2017)

Heterofunctional Poly(ethylene glycol) (PEG) Macroinitiator Enabling Controlled Synthesis of ABC Triblock Copolymers
por: Fliervoet, Lies A. L., et al.
Publicado: (2017)

Protein delivery nanosystem of six-arm copolymer poly(ε-caprolactone)–poly(ethylene glycol) for long-term sustained release
por: Duan, Jianwei, et al.
Publicado: (2018)

Structures and Applications of Thermoresponsive Hydrogels and Nanocomposite-Hydrogels Based on Copolymers with Poly (Ethylene Glycol) and Poly (Lactide-Co-Glycolide) Blocks
por: Maeda, Tomoki
Publicado: (2019)

3D Printability Assessment of Poly(octamethylene maleate (anhydride) citrate) and Poly(ethylene glycol) Diacrylate Copolymers for Biomedical Applications
por: Wales, Dominic J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e4s0og2i7rrer0h0t6ujmtcv8r