New effects of caffeine on corticotropin-releasing hormone (CRH)-induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH-R1/2, IP(3)-R, ACTH, MC-R2) and the neurogenic non-HPA axis (substance P, p75(NTR) and TrkA) in ex vivo human male androgenetic scalp hair follicles

BACKGROUND: Human hair is highly responsive to stress, and human scalp hair follicles (HFs) contain a peripheral neuroendocrine equivalent of the systemic hypothalamic–pituitary–adrenal (HPA) stress axis. Androgenetic alopecia (AGA) is supposed to be aggravated by stress. We used corticotropin-relea...

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Detalles Bibliográficos
Autores principales: Fischer, T.W., Bergmann, A., Kruse, N., Kleszczynski, K., Skobowiat, C., Slominski, A.T., Paus, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962141/
https://www.ncbi.nlm.nih.gov/pubmed/32271938
http://dx.doi.org/10.1111/bjd.19115

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