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The clinical heterogeneity of entirely nonenhancing CNS lymphoma: a case series

CNS lymphoma often presents with atypical imaging characteristics leading to delay in diagnosis and initiation of treatment. Among the most rarely reported of these is entirely nonenhancing CNS lymphoma, which is estimated at an incidence of about 1%. Here, we present three cases of nonenhancing CNS...

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Detalles Bibliográficos
Autores principales: Bowden, Stephen G, Munger, Daniel N, Thiessen, Jaclyn, Woll, S Cody Schoettler, Han, Seunggu J, Neuwelt, Edward A, Barajas, Ramon F, Ambady, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962175/
https://www.ncbi.nlm.nih.gov/pubmed/33322942
http://dx.doi.org/10.2217/cns-2020-0020
Descripción
Sumario:CNS lymphoma often presents with atypical imaging characteristics leading to delay in diagnosis and initiation of treatment. Among the most rarely reported of these is entirely nonenhancing CNS lymphoma, which is estimated at an incidence of about 1%. Here, we present three cases of nonenhancing CNS lymphoma in immune competent patients at both initial presentation and recurrence and in primary as well as secondary CNS lymphoma. Diffusion- and perfusion-weighted imaging was found helpful in diagnosis in some cases.