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Adult pilocytic astrocytoma in the molecular era: a comprehensive review
Adult pilocytic astrocytoma (PA) is less prevalent than pediatric PA and is associated with a worse prognosis. In a literature review, we found that 88.3% of the molecular alterations in adult PA are associated with MAPK pathway dysregulation. The most common alterations are fusions of BRAF. Underst...
Autores principales: | Gregory, Timothy A, Chumbley, Lyndon B, Henson, John W, Theeler, Brett J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962176/ https://www.ncbi.nlm.nih.gov/pubmed/33448230 http://dx.doi.org/10.2217/cns-2020-0027 |
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