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The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

TMEM132D is a human gene identified with multiple risk alleles for panic disorders, anxiety and major depressive disorders. Defining a conserved family of transmembrane proteins, TMEM132D and its homologs are still of unknown molecular functions. By generating loss-of-function mutants of the sole TM...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Jiang, Wei, Luo, Shuo, Yang, Xiaoyu, Wang, Changnan, Wang, Bingying, Dang, Yongjun, Shen, Yin, Ma, Dengke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962252/
https://www.ncbi.nlm.nih.gov/pubmed/33726789
http://dx.doi.org/10.1186/s13041-021-00767-w