Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer’s disease

SORL1 is strongly associated with both sporadic and familial forms of Alzheimer’s disease (AD), but a lack of information about alternatively spliced transcripts currently limits our understanding of the role of SORL1 in AD. Here, we describe a SORL1 transcript (SORL1-38b) characterized by inclusion...

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Detalles Bibliográficos
Autores principales: Monti, Giulia, Kjolby, Mads, Jensen, Anne Mette G., Allen, Mariet, Reiche, Juliane, Møller, Peter L., Comaposada-Baró, Raquel, Zolkowski, Bartlomiej E., Vieira, Cármen, Jørgensen, Margarita Melnikova, Holm, Ida E., Valdmanis, Paul N., Wellner, Niels, Vægter, Christian B., Lincoln, Sarah J., Nykjær, Anders, Ertekin-Taner, Nilüfer, Young, Jessica E., Nyegaard, Mette, Andersen, Olav M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962264/
https://www.ncbi.nlm.nih.gov/pubmed/33726851
http://dx.doi.org/10.1186/s40478-021-01140-7

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