Cargando…

Tumor mutation burden estimated by a 69-gene-panel is associated with overall survival in patients with diffuse large B-cell lymphoma

BACKGROUND: Tumor mutation burden (TMB) as estimated by cancer gene panels (CGPs) has been confirmed to be associated with prognosis and is effective in predicting clinical benefit from immune checkpoint blockade (ICB) in solid tumors. However, whether the TMB calculated by CGPs is associated with o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Cunte, Liu, Sichu, Jiang, Xinmiao, Huang, Ling, Chen, Feili, Wei, Xiaojun, Guo, Hanguo, Shao, Yang, Li, Yangqiu, Li, Wenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962318/ https://www.ncbi.nlm.nih.gov/pubmed/33722306 http://dx.doi.org/10.1186/s40164-021-00215-4

Ejemplares similares

TNFAIP3 mutation may be associated with favorable overall survival for patients with T-cell lymphoma
por: Chen, Cunte, et al.
Publicado: (2021)

Clinicopathological Characteristics and Mutational Profiling of Adult T-Cell Lymphoblastic Lymphoma in a Chinese Population
por: Chen, Feili, et al.
Publicado: (2020)

Clinical outcomes of newly diagnosed primary CNS lymphoma treated with ibrutinib‐based combination therapy: A real‐world experience of off‐label ibrutinib use
por: Chen, Feili, et al.
Publicado: (2020)

High expression of TMEM244 is associated with poor overall survival of patients with T-cell lymphoma
por: Chen, Cunte, et al.
Publicado: (2022)

TNFAIP3 mutation is an independent poor overall survival factor for patients with T‐cell acute lymphoblastic leukemia
por: Chen, Cunte, et al.
Publicado: (2022)

Low Expression of CD5 and CD6 Is Associated with Poor Overall Survival for Patients with T-Cell Malignancies
por: Sui, Songnan, et al.
Publicado: (2022)

Higher TOX Genes Expression Is Associated With Poor Overall Survival for Patients With Acute Myeloid Leukemia
por: Liang, Chaofeng, et al.
Publicado: (2021)

The importance of genomic predictors for clinical outcome of hematological malignancies
por: Chen, Cunte, et al.
Publicado: (2021)

Transcriptome-Based Co-Expression of BRD4 and PD-1/PD-L1 Predicts Poor Overall Survival in Patients With Acute Myeloid Leukemia
por: Chen, Cunte, et al.
Publicado: (2021)

Disulfiram, an aldehyde dehydrogenase inhibitor, works as a potent drug against sepsis and cancer via NETosis, pyroptosis, apoptosis, ferroptosis, and cuproptosis
por: Nie, Dingrui, et al.
Publicado: (2022)

High expression of LOC541471, GDAP1, SOD1, and STK25 is associated with poor overall survival of patients with acute myeloid leukemia
por: Yu, Xibao, et al.
Publicado: (2023)

BCL11B Mutations Are Associated with Higher CD8+ T-Cell Percentage and Favorable Clinical Outcomes in Patients with T-Cell Acute Lymphoblastic Leukemia
por: Chen, Cunte, et al.
Publicado: (2023)

Optimizing the evaluation of gene-targeted panels for tumor mutational burden estimation
por: Li, Yawei, et al.
Publicado: (2021)

Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel
por: Carreras, Joaquim, et al.
Publicado: (2021)

Indonesian dengue burden estimates: review of evidence by an expert panel
por: WAHYONO, T. Y. M., et al.
Publicado: (2017)

High Co-Expression of PDCD1/TIGIT/CD47/KIR3DL2 in Bone Marrow Is Associated with Poor Prognosis for Patients with Myelodysplastic Syndrome
por: Zhong, Mengjun, et al.
Publicado: (2023)

Estimated global overweight and obesity burden in pregnant women based on panel data model
por: Chen, Cheng, et al.
Publicado: (2018)

Clinical characteristics and treatment of 69 patients with extranodal natural killer T-cell lymphoma
por: Guo, Yuyan, et al.
Publicado: (2016)

Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia
por: Li, Bo, et al.
Publicado: (2012)

Meta-analytical methods for estimating outcomes from overall response rate in patients with relapsed/refractory diffuse large B-cell lymphoma
por: Wang, Ling, et al.
Publicado: (2019)

Dialysis Efficiency of AN69, a Semisynthetic Membrane Not Well Suited for Diffusion
por: Herrera-Gutiérrez, M. E., et al.
Publicado: (2012)

Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation
por: Shen, Qi, et al.
Publicado: (2013)

Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells
por: Liu, Sichu, et al.
Publicado: (2015)

Generation of diffuse large B cell lymphoma-associated antigen-specific Vα6/Vβ13+T cells by TCR gene transfer
por: Yin, Qingsong, et al.
Publicado: (2011)

Influence of low tumor content on tumor mutational burden estimation by whole‐exome sequencing and targeted panel sequencing
por: Zhang, Wenxin, et al.
Publicado: (2021)

Expression patterns of immune checkpoints in acute myeloid leukemia
por: Chen, Cunte, et al.
Publicado: (2020)

A Clinical Prediction Model of Overall Survival for Patients with Cervical Cancer Aged 25–69 Years
por: Fan, Wenli, et al.
Publicado: (2023)

Outcomes of fertility preservation treatments in patients with endometrial cancer with different molecular classifications based on an NGS panel
por: Xu, Yan, et al.
Publicado: (2023)

Dionysus in 69 /
Publicado: (1970)

The Tumor Mutational Burden of Chinese Advanced Cancer Patients Estimated by a 381-cancer-gene Panel
por: Zhuang, Wu, et al.
Publicado: (2018)

Age-Related Immune Profile of the T Cell Receptor Repertoire, Thymic Recent Output Function, and miRNAs
por: Xu, Yan, et al.
Publicado: (2020)

Human Leukocyte Antigen Class I and II Alleles and Overall Survival in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma
por: Lu, Yani, et al.
Publicado: (2011)

69. Exponential Increases in Cost, Competitiveness, and Complexity: The Integrated Plastic Surgery Match Burden
por: Paul Singh, Nikhi, et al.
Publicado: (2023)

Specific TCR profiles predict clinical outcome of adjuvant EGFR-TKIs for resected EGFR-mutant non-small cell lung cancer
por: Liu, Si-Yang Maggie, et al.
Publicado: (2023)

Estimating the Burden of Illness of Relapsed Follicular Lymphoma and Marginal Zone Lymphoma in Ontario, Canada
por: Kuruvilla, John, et al.
Publicado: (2023)

Disease burden of prostate cancer from 2014 to 2019 in the United States: estimation from the Global Burden of Disease Study 2019 and Medical Expenditure Panel Survey
por: Lin, Shen, et al.
Publicado: (2023)

Association of progression-free or event-free survival with overall survival in diffuse large B-cell lymphoma after immunochemotherapy: a systematic review
por: Zhu, Jie, et al.
Publicado: (2020)

The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia
por: Shen, Qi, et al.
Publicado: (2012)

The characteristic expression pattern of BMI-1 and SALL4 genes in placenta tissue and cord blood
por: Chen, Shaohua, et al.
Publicado: (2013)

Identification of a four-gene panel predicting overall survival for lung adenocarcinoma
por: Li, Chunyu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kk6tnick2dc3c6ck3minb765tm