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Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a tumor deriving from nasopharyngeal epithelium. Peptidyl-arginine deiminase 4 (PAD4) is a vital mediator of histone citrullination and plays an essential role in regulating disease process. Radiotherapy is an essential method to treat NPC. In this resea...

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Detalles Bibliográficos
Autores principales:	Chen, Hao, Luo, Min, Wang, Xiangping, Liang, Ting, Huang, Chaoyuan, Huang, Changjie, Wei, Lining
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962337/ https://www.ncbi.nlm.nih.gov/pubmed/33726680 http://dx.doi.org/10.1186/s11658-021-00251-2

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