Cargando…

Constitutive and Regulated Shedding of Soluble FGF Receptors Releases Biologically Active Inhibitors of FGF-2

The identification of soluble fibroblast growth factor (FGF) receptors in blood and the extracellular matrix has led to the prediction that these proteins modulate the diverse biological activities of the FGF family of ligands in vivo. A recent structural characterization of the soluble FGF receptor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hanneken, Anne, Mercado, Maluz, Maher, Pamela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962449/ https://www.ncbi.nlm.nih.gov/pubmed/33800200 http://dx.doi.org/10.3390/ijms22052712

Ejemplares similares

Shedding Light on the Complex Regulation of FGF23
por: Vervloet, Marc G.
Publicado: (2022)

Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development
por: Miyake, Ayumi, et al.
Publicado: (2013)

FGF19 subfamily members: FGF19 and FGF21
por: Dolegowska, Katarzyna, et al.
Publicado: (2019)

FGF-23 in bone biology
por: Wesseling-Perry, Katherine
Publicado: (2009)

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition
por: Allen, Benjamin L., et al.
Publicado: (2001)

Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
por: Allen, Benjamin L., et al.
Publicado: (2003)

Soluble Expression of Disulfide Bond Containing Proteins FGF15 and FGF19 in the Cytoplasm of Escherichia coli
por: Kong, Bo, et al.
Publicado: (2014)

Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho
por: Aaldijk, Alexandra S., et al.
Publicado: (2023)

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2
Publicado: (1996)

The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall
por: Boylan, Michael, et al.
Publicado: (2020)

Mechanism of FGF receptor dimerization and activation
por: Sarabipour, Sarvenaz, et al.
Publicado: (2016)

Structural Biology of the FGF7 Subfamily
por: Zinkle, Allen, et al.
Publicado: (2019)

Regulation of Fgf15 expression in the intestine by glucocorticoid receptor
por: Jia, Kunzhi, et al.
Publicado: (2019)

Heparin oligosaccharides: inhibitors of the biological activity of bFGF on Caco-2 cells.
por: Jayson, G. C., et al.
Publicado: (1997)

FGF19 and FGF21: In NASH we trust
por: Talukdar, Saswata, et al.
Publicado: (2020)

Ghrelin Ameliorates Traumatic Brain Injury by Down-Regulating bFGF and FGF-BP
por: Shao, Xuefei, et al.
Publicado: (2018)

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
por: Shamsi, Farnaz, et al.
Publicado: (2020)

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate
Publicado: (1992)

Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia
por: Mace, Maria L., et al.
Publicado: (2017)

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism
por: Takeshita, Ai, et al.
Publicado: (2018)

Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation
por: Takashi, Yuichi, et al.
Publicado: (2019)

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors
por: Feng, Shu, et al.
Publicado: (2016)

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

Regulation of nutrient metabolism by nuclear receptor/FGF signaling pathways
por: Kliewer, Steven A, et al.
Publicado: (2012)

FGF19 and FGF21 for the Treatment of NASH—Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human
por: Henriksson, Emma, et al.
Publicado: (2020)

FUBP3 interacts with FGF9 3′ microsatellite and positively regulates FGF9 translation
por: Gau, Bing-Huang, et al.
Publicado: (2011)

FGF-2 Deficiency Does Not Influence FGF Ligand and Receptor Expression during Development of the Nigrostriatal System
por: Ratzka, Andreas, et al.
Publicado: (2011)

Analysis of FGF-Dependent and FGF-Independent Pathways in Otic Placode Induction
por: Yang, Lu, et al.
Publicado: (2013)

Expression of FGF8, FGF18, and FGFR4 in Gastroesophageal Adenocarcinomas
por: Jomrich, Gerd, et al.
Publicado: (2019)

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells
Publicado: (1994)

Neurons produce FGF2 and VEGF and secrete them at least in part by shedding extracellular vesicles
por: Schiera, Gabriella, et al.
Publicado: (2007)

An Essential Requirement for Fgf10 in Pinna Extension Sheds Light on Auricle Defects in LADD Syndrome
por: Zhang, Yang, et al.
Publicado: (2020)

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
por: Agrawal, Archita, et al.
Publicado: (2018)

Advances in Biological Functions and Clinical Studies of FGF21
por: Lin, Wei, et al.
Publicado: (2021)

High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells--implications for the modulation of FGF-2
Publicado: (1995)

Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors
por: Chen, Zuyao, et al.
Publicado: (2023)

Phosphate and FGF-23
por: Jüppner, Harald
Publicado: (2011)

FGF23 and inflammation
por: Sharaf El Din, Usama A A, et al.
Publicado: (2017)

The FGF metabolic axis
por: Li, Xiaokun
Publicado: (2019)

Interactions of sclerostin with FGF23, soluble klotho and vitamin D in renal transplantation
por: Tartaglione, Lida, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4i1if36goku8c7ur45qhpj5tuu