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Ceramide Synthase 2 Null Mice Are Protected from Ovalbumin-Induced Asthma with Higher T Cell Receptor Signal Strength in CD4+ T Cells

(1) Background: six mammalian ceramide synthases (CerS1–6) determine the acyl chain length of sphingolipids (SLs). Although ceramide levels are increased in murine allergic asthma models and in asthmatic patients, the precise role of SLs with specific chain lengths is still unclear. The role of CerS...

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Detalles Bibliográficos
Autores principales:	Shin, Sun-Hye, Cho, Kyung-Ah, Yoon, Hee-Soo, Kim, So-Yeon, Kim, Hee-Yeon, Pewzner-Jung, Yael, Jung, Sung-Ae, Park, Woo-Jae, Futerman, Anthony H., Park, Joo-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962461/ https://www.ncbi.nlm.nih.gov/pubmed/33800208 http://dx.doi.org/10.3390/ijms22052713

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