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Alternative RNA degradation pathways by the exonuclease Pop2p from Saccharomyces cerevisiae
The 3′ to 5′ exonuclease Pop2p (Caf1p) is part of the CCR4-NOT deadenylation complex that removes poly(A) tails from mRNAs in cells. Pop2p is structurally conserved in eukaryotes, but Saccharomyces cerevisiae Pop2p harbors noncanonical amino acids in its catalytic center. The enzymatic properties of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962489/ https://www.ncbi.nlm.nih.gov/pubmed/33408095 http://dx.doi.org/10.1261/rna.078006.120 |