Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues

In this study, we review mechanoregulatory roles for perlecan in load-bearing connective tissues. Perlecan facilitates the co-acervation of tropoelastin and assembly of elastic microfibrils in translamellar cross-bridges which, together with fibrillin and elastin stabilise the extracellular matrix o...

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Detalles Bibliográficos
Autores principales: Guilak, Farshid, Hayes, Anthony J., Melrose, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962540/
https://www.ncbi.nlm.nih.gov/pubmed/33800241
http://dx.doi.org/10.3390/ijms22052716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962540/
https://www.ncbi.nlm.nih.gov/pubmed/33800241
http://dx.doi.org/10.3390/ijms22052716

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