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The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics
Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. TNF-α binds to two different receptors, which initiate signal tr...
Autores principales: | Jang, Dan-in, Lee, A-Hyeon, Shin, Hye-Yoon, Song, Hyo-Ryeong, Park, Jong-Hwi, Kang, Tae-Bong, Lee, Sang-Ryong, Yang, Seung-Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962638/ https://www.ncbi.nlm.nih.gov/pubmed/33800290 http://dx.doi.org/10.3390/ijms22052719 |
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