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Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) has a poor outcome compared to the other major breast cancer subtypes and new therapies are needed. We sought to clarify the functions of a ubiquitous protein, Annexin A1, in the development and progression of TNBC. We found that Annexin A1 expres...

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Detalles Bibliográficos
Autores principales: Johnstone, Cameron N., Tu, Yan, Langenbach, Shenna, Baloyan, David, Pattison, Andrew D., Lock, Peter, Britt, Kara L., Lehmann, Brian D., Beilharz, Traude H., Ernst, Matthias, Anderson, Robin L., Stewart, Alastair G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962654/
https://www.ncbi.nlm.nih.gov/pubmed/33800279
http://dx.doi.org/10.3390/cancers13051154