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Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro

Cardiotoxicity is one of the main side effects of doxorubicin (Dox) treatment. Dox could induce oxidative stress, leading to an opening of the mitochondrial permeability transition pore (mPTP) and apoptosis in cardiomyocytes. Previous studies have shown that Cryptotanshinone (Cts) has potential card...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoping, Sun, Qianbin, Jiang, Qianqian, Jiang, Yanyan, Zhang, Yawen, Cao, Jing, Lu, Linghui, Li, Chun, Wei, Peng, Wang, Qiyan, Wang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962658/ https://www.ncbi.nlm.nih.gov/pubmed/33800264 http://dx.doi.org/10.3390/molecules26051460

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