The need for polygenic score reporting standards in evidence-based practice: lipid genetics use case

Polygenic scores (PGS) are used to quantify the genetic predisposition for heritable traits, with hypothesized utility for personalized risk assessments. Lipid PGS are primed for clinical translation, but evidence-based practice changes will require rigorous PGS standards to ensure reproducibility a...

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Detalles Bibliográficos
Autores principales: Wand, Hannah, Knowles, Joshua W., Clarke, Shoa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
GENETICS AND MOLECULAR BIOLOGY: Edited by Robert A. Hegele
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962796/
https://www.ncbi.nlm.nih.gov/pubmed/33538426
http://dx.doi.org/10.1097/MOL.0000000000000733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962796/
https://www.ncbi.nlm.nih.gov/pubmed/33538426
http://dx.doi.org/10.1097/MOL.0000000000000733

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