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The need for polygenic score reporting standards in evidence-based practice: lipid genetics use case
Polygenic scores (PGS) are used to quantify the genetic predisposition for heritable traits, with hypothesized utility for personalized risk assessments. Lipid PGS are primed for clinical translation, but evidence-based practice changes will require rigorous PGS standards to ensure reproducibility a...
Autores principales: | Wand, Hannah, Knowles, Joshua W., Clarke, Shoa L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962796/ https://www.ncbi.nlm.nih.gov/pubmed/33538426 http://dx.doi.org/10.1097/MOL.0000000000000733 |
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