Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies

Membrane proteins such as G protein-coupled receptors (GPCRs) exert fundamental biological functions and are involved in a multitude of physiological responses, making these receptors ideal drug targets. Drug discovery programs targeting GPCRs have been greatly facilitated by the emergence of high-r...

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Detalles Bibliográficos
Autores principales: Waltenspühl, Yann, Ehrenmann, Janosch, Klenk, Christoph, Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962830/
https://www.ncbi.nlm.nih.gov/pubmed/33800379
http://dx.doi.org/10.3390/molecules26051465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962830/
https://www.ncbi.nlm.nih.gov/pubmed/33800379
http://dx.doi.org/10.3390/molecules26051465

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