19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), an ent-abietane diterpene diepoxide, inhibits the growth of bladder cancer T24 cells through DNA damage

Diterpenoids jolkinolide A and B, were first isolated from Euphorbia fischeriana. In our previous research, 19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), a derivative of jolkinolides, was synthesized as a novel ent -abietane diterpene diepoxide. In this study, 19-BJB showed strong in vitro activity a...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Yang, Juan-Cheng, Jang, Yeong-Jiunn, Chen, Guan-Yu, Zhang, Ya-Jing, Dai, Yun-Hao, Zhang, Da-Yong, Wu, Yang-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963099/
https://www.ncbi.nlm.nih.gov/pubmed/33724994
http://dx.doi.org/10.1371/journal.pone.0248468

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