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Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

SIMPLE SUMMARY: Epithelial to mesenchymal transition (EMT) is a mechanism endowing tumor cells with aggressive properties and escape immune surveillance. Here, we reported that activating EMT process in breast cancer cells upregulates CMTM6, an essential protein required for cell surface expression...

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Detalles Bibliográficos
Autores principales: Xiao, Malina, Hasmim, Meriem, Lequeux, Audrey, Moer, Kris Van, Tan, Tuan Zea, Gilles, Christine, Hollier, Brett G., Thiery, Jean Paul, Berchem, Guy, Janji, Bassam, Noman, Muhammad Zaeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963182/
https://www.ncbi.nlm.nih.gov/pubmed/33803139
http://dx.doi.org/10.3390/cancers13051165