Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

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Antibodies are a potential therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but the risk of the virus evolving to escape them remains unclear. Here we map how all mutations to the receptor binding domain (RBD) of SARS-CoV-2 affect binding by the antibodies in the REGN-COV2 c...

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Detalles Bibliográficos
Autores principales: Starr, Tyler N., Greaney, Allison J., Addetia, Amin, Hannon, William W., Choudhary, Manish C., Dingens, Adam S., Li, Jonathan Z., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963219/
https://www.ncbi.nlm.nih.gov/pubmed/33495308
http://dx.doi.org/10.1126/science.abf9302
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