Cargando…

Early growth response 2 (EGR2) is a novel regulator of the senescence programme

Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programmes, the key regulators driving p16 and ARF transcription remain largely underexplored. Using siRNA screening fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tyler, Eleanor J., Gutierrez del Arroyo, Ana, Hughes, Bethany K., Wallis, Ryan, Garbe, James C., Stampfer, Martha R., Koh, Jim, Lowe, Robert, Philpott, Michael P., Bishop, Cleo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963333/
https://www.ncbi.nlm.nih.gov/pubmed/33547862
http://dx.doi.org/10.1111/acel.13318

Ejemplares similares