Cargando…
Early growth response 2 (EGR2) is a novel regulator of the senescence programme
Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programmes, the key regulators driving p16 and ARF transcription remain largely underexplored. Using siRNA screening fo...
Autores principales: | Tyler, Eleanor J., Gutierrez del Arroyo, Ana, Hughes, Bethany K., Wallis, Ryan, Garbe, James C., Stampfer, Martha R., Koh, Jim, Lowe, Robert, Philpott, Michael P., Bishop, Cleo L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963333/ https://www.ncbi.nlm.nih.gov/pubmed/33547862 http://dx.doi.org/10.1111/acel.13318 |
Ejemplares similares
-
Cellular senescence mediated by p16(INK4A)-coupled miRNA pathways
por: Overhoff, Marita G., et al.
Publicado: (2014) -
Yearning for machine learning: applications for the classification and characterisation of senescence
por: Hughes, Bethany K., et al.
Publicado: (2023) -
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
por: Lowe, Robert, et al.
Publicado: (2015) -
Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
por: Wallis, Ryan, et al.
Publicado: (2022) -
Current Understanding of the Role of Senescent Melanocytes in Skin Ageing
por: Hughes, Bethany K., et al.
Publicado: (2022)