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Bardet–Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome

Certain ciliary signaling proteins couple with the BBSome, a conserved complex of Bardet–Biedl syndrome (BBS) proteins, to load onto retrograde intraflagellar transport (IFT) trains for their removal out of cilia in Chlamydomonas reinhardtii. Here, we show that loss of the Arf-like 6 (ARL6) GTPase B...

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Detalles Bibliográficos
Autores principales: Liu, Yan-Xia, Xue, Bin, Sun, Wei-Yue, Wingfield, Jenna L, Sun, Jun, Wu, Mingfu, Lechtreck, Karl F, Wu, Zhenlong, Fan, Zhen-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963478/
https://www.ncbi.nlm.nih.gov/pubmed/33587040
http://dx.doi.org/10.7554/eLife.59119

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