Cargando…

Microglial trogocytosis and the complement system regulate axonal pruning in vivo

Partial phagocytosis—called trogocytosis—of axons by microglia has been documented in ex vivo preparations but has not been directly observed in vivo. The mechanisms that modulate microglial trogocytosis of axons and its function in neural circuit development remain poorly understood. Here, we direc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Tony KY, Ruthazer, Edward S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963485/
https://www.ncbi.nlm.nih.gov/pubmed/33724186
http://dx.doi.org/10.7554/eLife.62167

Ejemplares similares