Cargando…
No Early Effect of Intrathecal Rituximab in Progressive Multiple Sclerosis (EFFRITE Clinical Trial)
BACKGROUND: The progressive phase of multiple sclerosis (MS) is characterized by an intrathecal (IT) compartmentalization of inflammation, involving B-cells within meningeal follicles, and resisting all the available immunosuppressive treatments. A new therapeutic paradigm may be to target this infl...
Autores principales: | Bonnan, Mickael, Ferrari, Sylvie, Courtade, Henri, Money, Paul, Desblache, Pauline, Barroso, Bruno, Debeugny, Stéphane |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7964121/ https://www.ncbi.nlm.nih.gov/pubmed/33763241 http://dx.doi.org/10.1155/2021/8813498 |
Ejemplares similares
-
Estimation of intrathecal IgG synthesis: simulation of the risk of underestimation
por: Bonnan, Mickael, et al.
Publicado: (2018) -
Intrathecal IgG Synthesis: A Resistant and Valuable Target for Future Multiple Sclerosis Treatments
por: Bonnan, Mickael
Publicado: (2015) -
Does Disease-Irrelevant Intrathecal Synthesis in Multiple Sclerosis Make Sense in the Light of Tertiary Lymphoid Organs?
por: Bonnan, Mickael
Publicado: (2014) -
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
por: Komori, Mika, et al.
Publicado: (2016) -
Compartmentalized intrathecal immunoglobulin synthesis during HIV infection — A model of chronic CNS inflammation?
por: Bonnan, Mickael, et al.
Publicado: (2015)