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Insulin granule biogenesis and exocytosis

Insulin is produced by pancreatic β-cells, and once released to the blood, the hormone stimulates glucose uptake and suppresses glucose production. Defects in both the availability and action of insulin lead to elevated plasma glucose levels and are major hallmarks of type-2 diabetes. Insulin is sto...

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Detalles Bibliográficos
Autores principales: Omar-Hmeadi, Muhmmad, Idevall-Hagren, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966131/
https://www.ncbi.nlm.nih.gov/pubmed/33146746
http://dx.doi.org/10.1007/s00018-020-03688-4