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LncRNA HOTAIR Promotes Cancer Stem-Like Cells Properties by Sponging miR-34a to Activate the JAK2/STAT3 Pathway in Pancreatic Ductal Adenocarcinoma

INTRODUCTION: Pancreatic Ductal Adenocarcinoma (PDAC) stem cells (CSCs) play a vital role in the occurrence, development and recurrence of PDAC. Previous studies have shown that long non-coding RNAs (lncRNA) are closely associated with occurrence and development of malignant tumors. Among them, a Ln...

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Detalles Bibliográficos
Autores principales: Deng, Shikang, Wang, Junfeng, Zhang, Li, Li, Jiao, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966354/
https://www.ncbi.nlm.nih.gov/pubmed/33737813
http://dx.doi.org/10.2147/OTT.S286666

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