Single-copy detection of somatic variants from solid and liquid biopsy

Accurate detection of somatic variants, against a background of wild-type molecules, is essential for clinical decision making in oncology. Existing approaches, such as allele-specific real-time PCR, are typically limited to a single target gene and lack sensitivity. Alternatively, next-generation s...

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Detalles Bibliográficos
Autores principales: Silva, Ana-Luisa, Powalowska, Paulina Klaudyna, Stolarek, Magdalena, Gray, Eleanor Ruth, Palmer, Rebecca Natalie, Herman, Bram, Frayling, Cameron Alexander, Balmforth, Barnaby William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966381/
https://www.ncbi.nlm.nih.gov/pubmed/33727644
http://dx.doi.org/10.1038/s41598-021-85545-3

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