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Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity

Reprogramming tumor infiltrating myeloid cells to elicit pro-inflammatory responses is an exciting therapeutic maneouver to improve anti-tumor responses. We recently demonstrated that a distinct microtubule-targeting drug, plinabulin—a clinical-stage novel agent—modulates dendritic cell maturation a...

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Detalles Bibliográficos
Autores principales: Natoli, Marina, Herzig, Petra, Pishali Bejestani, Elham, Buchi, Melanie, Ritschard, Reto, Lloyd, G. Kenneth, Mohanlal, Ramon, Tonra, James R., Huang, Lan, Heinzelmann, Viola, Trüb, Marta, Zippelius, Alfred, Kashyap, Abhishek S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966525/
https://www.ncbi.nlm.nih.gov/pubmed/33747968
http://dx.doi.org/10.3389/fonc.2021.644608

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