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Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity
Reprogramming tumor infiltrating myeloid cells to elicit pro-inflammatory responses is an exciting therapeutic maneouver to improve anti-tumor responses. We recently demonstrated that a distinct microtubule-targeting drug, plinabulin—a clinical-stage novel agent—modulates dendritic cell maturation a...
Autores principales: | Natoli, Marina, Herzig, Petra, Pishali Bejestani, Elham, Buchi, Melanie, Ritschard, Reto, Lloyd, G. Kenneth, Mohanlal, Ramon, Tonra, James R., Huang, Lan, Heinzelmann, Viola, Trüb, Marta, Zippelius, Alfred, Kashyap, Abhishek S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966525/ https://www.ncbi.nlm.nih.gov/pubmed/33747968 http://dx.doi.org/10.3389/fonc.2021.644608 |
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