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Hypoxanthine Induces Muscular ATP Depletion and Fatigue via UCP2

Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle remai...

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Detalles Bibliográficos
Autores principales: Yin, Cong, Ma, Zewei, Li, Fan, Duan, Chen, Yuan, Yexian, Zhu, Canjun, Wang, Lina, Zhu, Xiaotong, Wang, Songbo, Gao, Ping, Shu, Gang, Zhang, Huihua, Jiang, Qingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966526/
https://www.ncbi.nlm.nih.gov/pubmed/33746782
http://dx.doi.org/10.3389/fphys.2021.647743