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Targeting the Kaposi’s sarcoma-associated herpesvirus genome with the CRISPR-Cas9 platform in latently infected cells

BACKGROUND: Kaposi’s sarcoma-associated herpesvirus (KSHV) is a transforming gammaherpesvirus. Like other herpesviruses, KSHV infection is for life long and there is no treatment that can cure patients from the virus. In addition, there is an urgent need to target viral genes to study their role dur...

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Detalles Bibliográficos
Autores principales: Haddad, Coral Orel, Kalt, Inna, Shovman, Yehuda, Xia, Lei, Schlesinger, Yehuda, Sarid, Ronit, Parnas, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966637/
https://www.ncbi.nlm.nih.gov/pubmed/33731154
http://dx.doi.org/10.1186/s12985-021-01527-x