Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis

BACKGROUND: Multiple sclerosis (MS), an autoimmune disease of the central nervous system (CNS), can be suppressed in its early stages but eventually becomes clinically progressive and unresponsive to therapy. Here, we investigate whether the therapeutic resistance of progressive MS can be attributed...

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Detalles Bibliográficos
Autores principales: Kaufmann, Max, Evans, Hayley, Schaupp, Anna-Lena, Engler, Jan Broder, Kaur, Gurman, Willing, Anne, Kursawe, Nina, Schubert, Charlotte, Attfield, Kathrine E., Fugger, Lars, Friese, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Clinical and Translational Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966680/
https://www.ncbi.nlm.nih.gov/pubmed/33748804
http://dx.doi.org/10.1016/j.medj.2021.01.006

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