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Engineering of Aeromonas caviae Polyhydroxyalkanoate Synthase Through Site-Directed Mutagenesis for Enhanced Polymerization of the 3-Hydroxyhexanoate Unit

Polyhydroxyalkanoate (PHA) synthase is an enzyme that polymerizes the acyl group of hydroxyacyl-coenzyme A (CoA) substrates. Aeromonas caviae PHA synthase (PhaC(Ac)) is an important biocatalyst for the synthesis of a useful PHA copolymer, poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-...

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Detalles Bibliográficos
Autores principales:	Harada, Ken, Kobayashi, Shingo, Oshima, Kanji, Yoshida, Shinichi, Tsuge, Takeharu, Sato, Shunsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966705/ https://www.ncbi.nlm.nih.gov/pubmed/33748082 http://dx.doi.org/10.3389/fbioe.2021.627082

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